San Francisco streets are reeling from deadly drug 20x more powerful than fentanyl
San Francisco is facing a crisis due to a new drug called isotonitazene, or ISO, which is twenty times more potent than fentanyl. Health officials have reported that ISO has already claimed lives and is being mixed with other synthetic opioids, making it even more dangerous. The Drug Enforcement Administration has issued warnings about the rising popularity of ISO and its potential to cause fatal overdoses.
- ▪ISO is twenty times more potent than fentanyl and has been linked to overdose deaths in San Francisco.
- ▪The drug is often undetectable in standard tests for fentanyl, increasing its danger.
- ▪Health officials are alarmed by the rising popularity of ISO among users in the Tenderloin district.
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| Original publisher | California Post |
| Canonical URL | https://nypost.com/2026/06/05/us-news/san-francisco-streets-are-reeling-from-deadly-drug-20x-more-powerful-than-fentanyl/ |
| Publication time | Fri, 05 Jun 2026 20:03:32 -0400 |
| Retrieval time | 2026-06-06T00:43:00.622Z |
| Last seen | 2026-06-06T00:43:00.622Z |
| Headline source | Publisher (no WeSearch rewrite) |
| Excerpt source | publisher body |
| Excerpt method | First ~120 words (~800 chars) of extracted publisher body, fair-use limited. |
| Summary | WeSearch · cerebras-chat (WeSearch summarizer) |
| Summary source text | contentText |
| Citation coverage | Summary is a WeSearch-generated derivative; primary citation is the original publisher URL. |
| Cluster | cV-wvXmu_GQR |
| Cluster logic | Grouped by semantic title/content similarity across sources within a rolling window. Same-publisher template collisions are excluded from coverage comparison. |
| Ranking reason | Story pages are not engagement-ranked. Hub feeds use recency, with optional source-diversified chronological ordering (cap consecutive stories per source). No personalized ranking. |
| Publisher visit | Yes — open original |
| Substitutes article? | No — link-out required for full text |
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| Indexing | May the item be indexed (stored, ranked, made findable)? | Allowed |
| Snippet | May a short excerpt of the publisher's text be shown? | Allowed |
| AI summary | May WeSearch generate its own short summary of the article? | Limited |
| Retrieval / RAG | May the content be exposed for third-party retrieval-augmented generation? | Not asserted |
| Model training | May the content be used to train AI models? | Not asserted |
| Commercial reuse | May the content be reused commercially? | Not permitted |
Basis: Derived from the published RSS/Atom feed. Contact: [email protected]. Reviewed: 2026-07-24.
Opening excerpt (first ~120 words) tap to expand
Metro San Francisco streets are reeling from deadly drug 20x more powerful than fentanyl By Ben Chapman Published June 5, 2026, 8:03 p.m. ET See more of our coverage in your search results. Add The California Post on Google The streets of San Francisco are awash with a new drug called ISO that’s twenty times more potent than deadly fentanyl – and officials are sounding the alarm. The killer counterfeit opioid isotonitazene – known on the streets as ISO – claimed its first life in the drug-ravaged city in April, San Francisco Health Department officials said in an alert issued that month. San Francisco health officials said ISO was blended with another synthetic opioid called cychlorphine in the overdose death announced April 23.
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Excerpt limited to ~120 words for fair-use compliance. The full article is at California Post.
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