1,700 new protein found in the "dark proteome" of previously overlooked DNA
A recent study has identified 1,700 new proteins in the so-called 'dark proteome' of human DNA, expanding our understanding of the human proteome. These proteins, which were previously overlooked, may play significant roles in various biological processes. The findings could have implications for medical research and the development of new therapies.
- ▪The study discovered 1,700 new proteins in the human 'dark proteome'.
- ▪These proteins were previously unrecognized and may influence biological functions.
- ▪The research could lead to advancements in medical therapies and understanding of human biology.
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| Original publisher | PubMed |
| Canonical URL | https://pubmed.ncbi.nlm.nih.gov/42092140/ |
| Publication time | Sun, 24 May 2026 08:01:36 +0000 |
| Retrieval time | 2026-05-24T08:07:31.211Z |
| Last seen | 2026-05-24T08:07:31.211Z |
| Headline source | Publisher (no WeSearch rewrite) |
| Excerpt source | publisher body |
| Excerpt method | First ~120 words (~800 chars) of extracted publisher body, fair-use limited. |
| Summary | WeSearch · cerebras-chat (WeSearch summarizer) |
| Summary source text | contentText |
| Citation coverage | Summary is a WeSearch-generated derivative; primary citation is the original publisher URL. |
| Cluster | 3YGKAM7ox2BM |
| Cluster logic | Grouped by semantic title/content similarity across sources within a rolling window. Same-publisher template collisions are excluded from coverage comparison. |
| Ranking reason | Story pages are not engagement-ranked. Hub feeds use recency, with optional source-diversified chronological ordering (cap consecutive stories per source). No personalized ranking. |
| Publisher visit | Yes — open original |
| Substitutes article? | No — link-out required for full text |
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| Indexing | May the item be indexed (stored, ranked, made findable)? | Allowed |
| Snippet | May a short excerpt of the publisher's text be shown? | Allowed |
| AI summary | May WeSearch generate its own short summary of the article? | Limited |
| Retrieval / RAG | May the content be exposed for third-party retrieval-augmented generation? | Not asserted |
| Model training | May the content be used to train AI models? | Not asserted |
| Commercial reuse | May the content be reused commercially? | Not permitted |
Basis: Derived from the published RSS/Atom feed. Contact: [email protected]. Reviewed: 2026-07-24.
Opening excerpt (first ~120 words) tap to expand
Nature Actions Search in PubMed Search in NLM Catalog Add to Search . 2026 May 6. doi: 10.1038/s41586-026-10459-x. Online ahead of print. Expanding the human proteome with microproteins and peptideins Eric W Deutsch # 1 , Leron W Kok # 2 3 , Jonathan M Mudge # 4 , Cristian F Valls # 5 6 , Irwin Jungreis # 7 8 , Jorge Ruiz-Orera 9 , Zhi Sun 1 , Ulrike Kusebauch 1 , Ivo Fierro-Monti 4 10 , Jennifer G Abelin 8 , M Mar Alba 11 12 , Julie L Aspden 13 , Sreejan Bandyopadhyay 14 , Kaushik Banerjee 5 6 , Pavel V Baranov 15 , Ariel A Bazzini 16 17 , Francis Bourassa 18 , Elspeth A Bruford 19 , Lorenzo Calviello 20 , Steven A Carr 8 , Anne-Ruxandra Carvunis 21 22 23 , Sonia Chothani 24 25 , Jim Clauwaert 5 , Kellie Dean 15 , Pouya Faridi 26 27 , Adam Frankish 4 , Amy Goodale 8 , Thomas Green 8 ,…
Excerpt limited to ~120 words for fair-use compliance. The full article is at PubMed.
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